Preheat your oven to 350°F (175°C) and grease a standard loaf pan with butter or non-stick spray.

In a small bowl, beat together the cream cheese, granulated sugar, and vanilla extract until smooth and creamy. Set aside.

In a large mixing bowl, whisk together melted butter and sugar until combined. Add eggs and remaining vanilla, then stir in milk.

In another bowl, whisk together flour, baking powder, and salt. Gradually fold dry ingredients into wet mixture until just combined.

Gently fold in the blueberries, ensuring they are evenly distributed.

Pour half of the batter into the greased pan, dollop half of cream cheese mixture, and swirl it in. Repeat with remaining batter and cream cheese.

Bake for about 60 minutes, checking for doneness with a toothpick.

Allow to cool in the pan for 10 minutes, then transfer to a wire rack to cool completely before slicing.