Prepare the ingredients by chopping onion and mincing garlic. Combine ground turkey, onion, garlic, cumin, chili powder, salt, and pepper in a bowl and mix until just combined.

Form the mixture into 4 equal patties, about ¼ pound each and ¾ inch thick, making an indentation in the center of each patty.

Preheat the grill or skillet over medium-high heat, reaching about 375°F (190°C). Add olive oil if using a skillet.

Cook patties on the grill or skillet for 5-6 minutes without moving, then flip and cook for another 5-6 minutes until the internal temperature reaches 165°F (75°C).

In the last minute of cooking, place a slice of cheese on each patty to melt.

Assemble your burgers by placing the patty on a bun, topped with avocado, salsa, and lettuce.

Serve and enjoy your Spicy Southwest Turkey Burgers!